FROMULATION AND EVALUATION OF HERBAL ANTIMICROBIAL CREAM OF CLITORIA TERNATEA FLOWER

Abstract

The present study focuses on the formulation and evaluation of an antimicrobial cream containing extract
of Clitoria ternatea flower. Herbal formulations have gained significant attention due to their safety,
effectiveness, minimal side effects, and natural origin. Clitoria ternatea is well known for its
antimicrobial, antioxidant, anti-inflammatory, and wound-healing properties because of the presence of
phyto-constituents such as flavonoids, tannins, alkaloids, glycosides, and anthocyanins. The aim of the
study was to develop a stable and effective topical antimicrobial cream using Clitoria ternatea flower
extract and to evaluate its pharmaceutical parameters. The antimicrobial cream was prepared by using
suitable ingredients such as stearic acid, cetyl alcohol, glycerin, triethanolamine, preservatives, and
purified water by the oil-in-water (O/W) emulsification method. The prepared formulation was evaluated
for various physicochemical parameters including color, odour, appearance, homogeneity, pH,
spreadability, washability, viscosity, stability, and antimicrobial activity. The pH of the cream was found
to be compatible with skin pH, indicating suitability for topical application. The formulation showed
good consistency, smooth texture, and satisfactory spreadability without causing irritation. The study
concludes that Clitoria ternatea flower can be effectively incorporated into a topical cream formulation
with good antimicrobial potential and acceptable pharmaceutical properties.